Posts Tagged ‘allergens’

Allergen Responses

25th August 2010 by Bronchitis No Comments

Allergy is described as an exaggerated reaction of the immune system to foreign bodies and substances that are not harmful to normal non-allergic individuals. The response by the immunity process is exaggerated as it treats these foreign bodies as threats to the health of the body, instead of discarding and getting rid of them love it normally would. This reaction is achievable if a certain reaction to the immune system is activated.

The mechanism of allergies begins with the so-called exaggerated reaction of the immunity process to antigens. Antigens are specific substances that trigger the immune system to release its antibodies. Once an antigen invades the body, the immunity process will attempt to work out the nature of antigen by identifying whether it is dangerous or not. In people who have not developed allergies, all antigens are not harmful.

All the same, for people who had antigens which underwent previous sensitization, selected antigens are treated by the body as threats. Among allergic people, the invasion of an antigen will trigger a number of immune response called allergic cascade. The outcome of that are allergic reactions and signs characterizing the specific allergy or the specific body part tormented by the antigen.

The antigen to which a person is allergic to is known as allergen which comes in varieties of animal dander, foods, drugs, chemical substances, pollens, dust mites and others.

Allergens can penetrate the body through various access points. These access points are essentially distinguished by the nature of the allergen. For example, nasal passages are the passageways for pollens, dust mites, dust, molds and different minute objects.

Allergens can likewise have a bearing on the body, but do not necessarily have to penetrate the inner body, through the contact with the skin or mucous membranes. Topical chemicals and substances are often the culprits of allergic responses on the skin. This hypersensitive reaction differs with other allergic responses as it only triggers cells of inflammation which are located on the superficial layers of the skin and not the specific antibody that reacts to allergens- the IgE.

Even so, for some substances, contact does not end with the skin, they occasionally seep through the underlying structures to cause more life-threatening allergic responses. There are also irritants that are injected to the body. These typically include materials that are injected mechanically or chemicals that insects carry. Lastly are the irritants that are ingested which compose of a variety of food that typically trigger allergic responses among humans, treatments and drugs. In over sensitive individuals, even water components may pose as allergens.

The allergic cascade happens in three phases. It begins with the invasion of a common substance of the body’s system. If the immune system detects it as harmless, it won’t respond aggressively, leading to the antigen’s elimination. However, if the immune system detects it as a threat, it will make IgE or immunoglobulin E, an antibody that reacts to allergens, in massive quantities. IgE in turn will plot the allergen as harmful and will build up immune responses to it in succeeding encounters.

After sensitization comes another encounter with the antigen. By this occasion, your body has already developed exaggerated responses. Attributable to the release off some chemicals into the bloodstream as it tries to eliminate the antigen, the body will go through the symptoms of the allergy.

These signs are the natural consequences of the immune response.

 

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